The persistence of ALG-125755 in mouse liver pharmacodynamics is associated with total siRNA and RISC binding siRNA
At the 2023 European Liver Conference (EASL 2023), researchers from the American clinical stage biopharmaceutical company AligosTherapeutics introduced another latest progress in the development of small interfering RNA (siRNA) ALG-125755 drugs,The pharmacodynamic persistence of ALG-125755 (a GalNAc binding siRNA) in mouse liver is related to the total siRNA and RNA inducible complex (RISC) binding siRNA.This study is sourced from Aligos Corporation, EASL2023The researchers introduced that the continuous disappearance of HBsAg (HBsAg) is required to achieve functional cure of chronic hepatitis B...
Notice of Clinical Trial Approval for Recombinant Human Adenovirus 5 Injection of Shanghai Pharmaceuticals Group Co., Ltd. Restructuring
Recombinant human adenovirus type 5 injection (trade name: Ankrui) is an oncolytic adenovirus anti-tumor drug that contains recombinant adenoviruses that can specifically replicate in tumor cells, cause tumor cell damage, lysis, and further activate immune responses to exert anti-tumor effects. Ankeri was approved for marketing in China in 2005, with an approved indication for advanced nasopharyngeal carcinoma...
Five major news: Great reversal, determination to produce and replace 23 types of core equipment nationwide! Huawei Upwind Turnover
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SpaceX expects to double its revenue to $8 billion in 2023
[Global Network Technology Comprehensive Report] On July 18, according to The Information, insiders said that SpaceX, a Space exploration technology company owned by Elon Musk, disclosed to some investors that it is expected that the company will achieve revenue of about 8 billion dollars (about 57.3 billion yuan at present) in 2023, about twice the revenue of the previous year...
Across China's Qinling Mountains, the Yangtze River and the Yellow River are "hand in hand" here
On July 16th, the national major water conservancy project - the Water Diversion from Han to Wei River Project - achieved initial water supply. The river water drawn from the Han River, the largest tributary of the Yangtze River, passed through the nearly 100 kilometer Qinling Tunnel and supplied the Wei River, the largest tributary of the Yellow River, thus achieving the "hand in hand" between the Yangtze River and the Yellow River in Guanzhong...
The coldest summer season for mobile phones: sales halved, inventory backlog, and single machine profits of tens of yuan
source |Tech Planetwriting |Wang Linsource |Figure insect creativityZhang Xiaofeng, who runs a mobile phone store in Inner Mongolia, did not welcome the expected summer. In the past, summer was one of the best-selling seasons for mobile phone brands (followed by winter vacation), with Q2 selling over 100 million phones throughout the summer at its peak...
9 articles were exploded from the factory! The Affiliated Hospital of Jining Medical University and the Second Affiliated Hospital of Lian Medical University will withdraw their papers
withdraw a contributionreal-time infoOfficial WeChatFor more exciting content, please contactPaper InformationIn December 2019, the Affiliated Hospital of Jining Medical University and the Second Affiliated Hospital of Dalian Medical UniversityEuropean review for formal and pharmaceutical sciences (Zone 3.3000/4)The title published online in the journal isEffectofatorvastatininpulmonaryarterialhypertensiinratthroughPI3K/AKTsignalingpathway(The effect of Atorvastatin on pulmonary hypertension in rats through PI3K/AKT signaling pathway)...
Astronaut Chen Dong has been undergoing closed training for 6 years, and the teacher has published a newspaper to search for and give birth to twin boys with his wife
In 2016, the Shenzhou 11 manned spacecraft won the sky. After the fairing was thrown away, the commander Jing Haipeng asked Chen Dong:Are you feeling goodCurious about the vast starry sky, Chen Dong couldn't conceal his excitement and loudly replied:CoolAt that time, Chen Dong was still a novice in exploring the universe...
The Chinese Academy of Sciences is no longer called "Chinese Academy of Sciences" for short
Recently, a notice of the Chinese Academy of Sciences on the modification of the abbreviation has aroused heated debate.The notice stated: "Both the full name and the short name of our academy are 'Chinese Academy of Sciences'...
The Early Water Diversion Project from Han to Wei Rivers Achieves "Hand in Hand" between the Yangtze River and the Yellow River
Source: Original manuscript by People's DailyPeople's Daily, Beijing, July 17 (Jiao Lei) On July 16, the national key water conservancy project - the Water Diversion from Han to Wei River Project officially opened to Xi'an, and the beautiful wish of the Han River flowing through the Runze Guanzhong area of the Qinling Mountains has become a reality. Among them, the Qinling Water Diversion Tunnel is a key control project for the entire Han to Wei River Diversion Project...
Numerical Study on the Enhancement Concept of Active and Passive Cycles by Wind Turbine Performance
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Not called 'Chinese Academy of Sciences'! Revised abbreviation of Chinese Academy of Sciences
Circular of the General Office of the Chinese Academy of Sciences on the Abbreviation of the Chinese Academy of SciencesOn July 11, the General Office of the Chinese Academy of Sciences sent a notice on the abbreviation of our academy to the whole academy, some of which are as follows:In accordance with the Notice of the Secretary Bureau of the General Office of the State Council on Printing and Distributing the Abbreviations of Institutions under the State Council (GBMH [2023] No. 18), the Secretary Bureau of the General Office of the State Council revised the abbreviation of our institute, which is referred to as the Chinese Academy of Sciences after revision...