The persistence of ALG-125755 in mouse liver pharmacodynamics is associated with total siRNA and RISC binding siRNA

The persistence of ALG-125755 in mouse liver pharmacodynamics is associated with total siRNA and RISC binding siRNA

At the 2023 European Liver Conference (EASL 2023), researchers from the American clinical stage biopharmaceutical company AligosTherapeutics introduced another latest progress in the development of small interfering RNA (siRNA) ALG-125755 drugs,The pharmacodynamic persistence of ALG-125755 (a GalNAc binding siRNA) in mouse liver is related to the total siRNA and RNA inducible complex (RISC) binding siRNA.This study is sourced from Aligos Corporation, EASL2023The researchers introduced that the continuous disappearance of HBsAg (HBsAg) is required to achieve functional cure of chronic hepatitis B...

Notice of Clinical Trial Approval for Recombinant Human Adenovirus 5 Injection of Shanghai Pharmaceuticals Group Co., Ltd. Restructuring

Notice of Clinical Trial Approval for Recombinant Human Adenovirus 5 Injection of Shanghai Pharmaceuticals Group Co., Ltd. Restructuring

Recombinant human adenovirus type 5 injection (trade name: Ankrui) is an oncolytic adenovirus anti-tumor drug that contains recombinant adenoviruses that can specifically replicate in tumor cells, cause tumor cell damage, lysis, and further activate immune responses to exert anti-tumor effects. Ankeri was approved for marketing in China in 2005, with an approved indication for advanced nasopharyngeal carcinoma...

Numerical Study on the Enhancement Concept of Active and Passive Cycles by Wind Turbine Performance

Numerical Study on the Enhancement Concept of Active and Passive Cycles by Wind Turbine Performance

//<<>>--NREL Phase VINREL Phase VI<<>>1.1...

Can straw be combined with water and electricity? Circular carbon sequestration greenhouse is very smart

Can straw be combined with water and electricity? Circular carbon sequestration greenhouse is very smart

Science and Technology Daily reporter Zhao HanbinIn the mountainous areas of southwestern China, many rural areas are characterized by poor soil quality, lack of water resources, and varying degrees of pollution. At the same time, although extensive rural power networks have been established in various regions, the tight situation of some remote village groups and farmers' "power grid ends" has not yet been fully alleviated...

China's first large-diameter double shield earth pressure combined shield machine started in Guangzhou

China's first large-diameter double shield earth pressure combined shield machine started in Guangzhou

On July 13, the first large-diameter double shield earth pressure combined shield machine independently developed by China, "Tiebing Guanghua No. 6", successfully started at the No...

Do Europe and America want to produce gallium themselves? Shandong Binzhou's annual electricity consumption of 123.5 billion kilowatt hours directly scares them out

Do Europe and America want to produce gallium themselves? Shandong Binzhou's annual electricity consumption of 123.5 billion kilowatt hours directly scares them out

The ancient Chinese ancestor left many classic sayings to future generations, such as hitting the snake and hitting the seven inch mark, coming without disrespect, and so on.In recent years, some European and American countries used some unfounded reasons to restrict the development of China's Semiconductor industry, trying to hinder the progress of China's advanced industries, and then consolidate their position in competitive industries and their leadership in the global industry chain...

Should the Virtual Consciousness of 'The Mechanical Concubine' be Constrained by Ethical Norms

Should the Virtual Consciousness of 'The Mechanical Concubine' be Constrained by Ethical Norms

Wen|promiseEdit|promiseThe rapid development and technological progress of artificial intelligence are triggering profound reflections on ethical norms. As the technological community continues to break through the boundaries of innovation, the concept of virtual consciousness has become a highly concerned and researched field...

Reminder: Binding bank cards on WeChat may also pose serious security risks! Look early, avoid early!

Reminder: Binding bank cards on WeChat may also pose serious security risks! Look early, avoid early!

With the continuous development of the Internet, WeChat has also entered our lives and become an irreplaceable communication tool. It is precisely because WeChat is very convenient that both men, women, and children can easily control it...

The First Flat Panel New System Communication Test Satellite Developed by Harbin Institute of Technology Successfully Launched

The First Flat Panel New System Communication Test Satellite Developed by Harbin Institute of Technology Successfully Launched

On June 9, China's first flat plate type new system communication test satellite, "Longjiang No.3", was ignited and lifted off in the Jiuquan Satellite Launch Center by taking the Kuaizhou 1A solid carrier rocket...

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The "Taihang 110" heavy-duty gas turbine has passed the complete machine verification

Shenzhen, June 4th (Reporter Jiao Yang) - On the 4th, at CNOOC Shenzhen Power Plant, the "Taihang 110" heavy-duty gas turbine (code name AGT-110) independently developed by China Aerospace Development Corporation was operating normally. The display screen in the control room shows that the "Taihang 110" heavy-duty gas turbine has accumulated over 14000 equivalent hours of operation, with a single unit operating for over 7000 equivalent hours...

Huawei Releases the Smart and Easy All Optical Connection Strategy, Describing the Development Direction of the Optical Industry with 2+2+X

Huawei Releases the Smart and Easy All Optical Connection Strategy, Describing the Development Direction of the Optical Industry with 2+2+X

On June 1st, Huawei officially released its Smart Jian All Optical Connectivity Strategy and series of new products in Beijing. Facing the evolution of F5...

World's largest onshore impeller diameter wind turbine offline

World's largest onshore impeller diameter wind turbine offline

Science and Technology Daily News (Reporter Li Liyun): According to Mingyang Group, the MySE10.X-23X onshore wind turbine independently developed by Mingyang Intelligent officially went offline on May 26th...