Research Reveals the Structure and Self Inhibition Mechanism of Glycosylphosphatidylinositol Transamidase Complex Binding to Ligands

Research Reveals the Structure and Self Inhibition Mechanism of Glycosylphosphatidylinositol Transamidase Complex Binding to Ligands

[Source: Shanghai Municipal Government Today Shanghai Industry Information]Recently, NatureCommunications published online the research results of Li exemplary research group of the Center for Excellence and Innovation in Molecular Cell Science of the Chinese Academy of Sciences and Qu Qianhui research group of Fudan UniversityGlycosylphosphatidylinositol TransamidaseIlluminateGPI-APBiogenesis reveals the structural basis of glycosylphosphatidylinositol (GPI) transamidase (GPI-T) complexes for recognizing a wide range of substrates and the self inhibitory mechanism for preventing accidental shear.GPI modification is a common post translational modification in eukaryotes...

The Huake University team has made significant breakthroughs in scientific research and is the first internationally to achieve the overall magnetization and demagnetization of megawatt level permanent magnet wind turbines

The Huake University team has made significant breakthroughs in scientific research and is the first internationally to achieve the overall magnetization and demagnetization of megawatt level permanent magnet wind turbines

Huazhong University of Science and Technology team photo provided by Huazhong University of Science and TechnologyAccording to Xinhua News Agency, on October 8th, it was learned from Huazhong University of Science and Technology that the engineering and technical team of the National Pulse Strong Magnetic Field Science Center of Huazhong University of Science and Technology has recently successfully achieved the overall magnetization and demagnetization of the rotor of a 20 MW semi direct drive permanent magnet wind turbine, marking China's scientific research team being the first in the world to achieve the overall magnetization and demagnetization of the entire series of models of megawatt level permanent magnet wind turbines.It is reported that permanent magnet wind turbines are currently the main model used for wind power generation, and the permanent magnet pole is a key core component of permanent magnet motors, assembled from numerous magnetic steel...

Academician Chen Zijiang won the Walter Futterweit Clinical Research Excellence Award

Academician Chen Zijiang won the Walter Futterweit Clinical Research Excellence Award

On October 5-7, 2023, coinciding with the 20th anniversary of the release of the Rotterdam diagnostic criteria for polycystic ovary syndrome (PCOS), the AE-PCOS conference was held in Rotterdam, Netherlands. Academician Chen Zijiang was awarded the Walter Futterweit Clinical Research Excellence Award for his outstanding contributions in the research and clinical practice of polycystic ovary syndrome...

Chinese scholars have obtained the latest research results: 70% of breast cancer patients may benefit from

Chinese scholars have obtained the latest research results: 70% of breast cancer patients may benefit from "classified treatment"

China News Network, Shanghai, October 8 (Reporter Chen Jing) Among breast cancer patients, nearly 70% of newly diagnosed patients and more than half of patients with recurrence and metastasis clinically suffer from cavity type breast cancer.The reporter learned on the 8th that Chinese scholars took five years to tackle key problems, took the lead in drawing the "multi-ethnic panorama map of cavity surface breast cancer", and proposed the precise treatment strategy based on the "Fudan cavity surface quartering"...

The latest research result from a Canadian research team: This weight loss drug increases the risk of pancreatitis by 900%!

The latest research result from a Canadian research team: This weight loss drug increases the risk of pancreatitis by 900%!

The internationally renowned medical journal "Journal of the American Medical Association" published an article on weight loss drugs on the 5th, introducing the latest research results of a researcher. The research results have poured cold water on the currently popular GLP-1 type of weight loss drugs...

Publicity! Pudong to Build Shanghai Base of China Giant Panda Protection and Research Center

Publicity! Pudong to Build Shanghai Base of China Giant Panda Protection and Research Center

Pudong will build the Shanghai Base of the China Giant Panda Protection and Research Center. According to the "Regulations on the Planning and Publicity of Construction Engineering Design Schemes in Shanghai", the construction engineering planning and design scheme of the Shanghai Base of the China Giant Panda Protection and Research Center has been made public to the public...

The first systematic collection of rock samples from Zhuoyoufeng by Chinese scientific researchers

The first systematic collection of rock samples from Zhuoyoufeng by Chinese scientific researchers

The members of the Mineral Resources and Geological Environment Research Team of the High Altitude Comprehensive Research Team of the Second Qinghai Tibet Scientific Research on Zhuoyou Peak recently climbed up the mountain from Dingri County, Shigatse City, Tibet, at an altitude of 4950 meters, to reach the destination for rock sample collection - Zhuoyou Peak.Zhuoyou Peak has an altitude of 8201 meters and is the sixth highest peak in the world...

Apple may switch Safari's seamless search engine from Google to DuckDuckGo

Apple may switch Safari's seamless search engine from Google to DuckDuckGo

On October 7th, according to foreign media reports, insiders revealed that Apple has entered into negotiations with the search engine DuckDuckGo, hoping to replace the default search engine for Safari Browser's seamless mode from Google to DuckDuckGo.It is reported that Apple's move is related to Google's antitrust case, which involves allegations of Google abusing its power as a major search provider...

China's scientific research ship arrives at the North Pole for the first time, embarking on a new starting point for the Arctic Ocean scientific research in China

China's scientific research ship arrives at the North Pole for the first time, embarking on a new starting point for the Arctic Ocean scientific research in China

A month ago at 13:55 on September 5th, the scientific research team successfully arrived at the North Pole on the "Snow Dragon 2", marking the first time a Chinese scientific research ship has arrived at the North Pole, filling the gap in China's polar scientific research. Why did the research ship arrive at the North Pole after more than ten scientific explorations? How did the Snow Dragon 2 reach the North Pole?CCTV reporter Wang Nan from the headquarters:I am currently on the bridge of the polar ice breaker "Snow Dragon 2"...

(Technology) New Research Discovers the Deep Pathogenic Mechanism of Sporadic Alzheimer's Disease

(Technology) New Research Discovers the Deep Pathogenic Mechanism of Sporadic Alzheimer's Disease

Jerusalem, October 5th (Xinhua) - The Israeli Institute of Technology recently released a statement stating that an international team led by its researchers has found that the accumulation of toxic proteins in the brain of sporadic Alzheimer's disease patients is related to the failure of protein clearance mechanisms, and targeting specific proteins may alleviate the disease. The relevant paper was published in the UK journal Nature Communications...

In order to conduct scientific research in the

In order to conduct scientific research in the "Heavenly Palace", Chinese scientists have done these things

Superconductive technology, marine resources, aerospace technology, meteorological prediction, water conservancy and hydropowerExperts in the field, focusing on China's five most representative and practical sciences and technologies that benefit the peopleWhat is' strong 'for enriching the people and strengthening the countryTo lead the public to experience the spirit and charm behind China's technology and scientific research work.Director of Application Development Center, Center for Space Application Engineering and Technology, Chinese Academy of SciencesZhang WeiProfessor brings a speech:A firm step in China's space exploration...

China Youth Daily: Why Young Researchers Are Passionate about Chasing

China Youth Daily: Why Young Researchers Are Passionate about Chasing "Hats"

The talent "hat" that is hotly discussed in the technology industry mainly refers to talent programs and research projects funded by talents. The purpose of talent programs is to care for, select, and support talents, while research projects provide research funding for outstanding scientific and technological talents, playing a role in cultivating and motivating them...