The persistence of ALG-125755 in mouse liver pharmacodynamics is associated with total siRNA and RISC binding siRNA
At the 2023 European Liver Conference (EASL 2023), researchers from the American clinical stage biopharmaceutical company AligosTherapeutics introduced another latest progress in the development of small interfering RNA (siRNA) ALG-125755 drugs,The pharmacodynamic persistence of ALG-125755 (a GalNAc binding siRNA) in mouse liver is related to the total siRNA and RNA inducible complex (RISC) binding siRNA.This study is sourced from Aligos Corporation, EASL2023The researchers introduced that the continuous disappearance of HBsAg (HBsAg) is required to achieve functional cure of chronic hepatitis B...
Eli Lilly announces the complete phase III data of new drugs for Alzheimer's disease, which may compete with Eisai at the end of the year
TRAILBLAZER-ALZ2 Design of experiments and summary of results. Image source: Journal of the American Medical AssociationOn July 17 local time, the United States Lilly (LLY...
News says Samsung is collaborating with Japanese company MEIKO to develop smart rings
On July 18th, according to TheElec, Samsung has reached a partnership with Japanese company MEIKO to jointly promote the smart ring project.It is reported that MEIKO is mainly responsible for manufacturing printed circuit boards (PCBs) of smart rings for Samsung...
SpaceX expects to double its revenue to $8 billion in 2023
[Global Network Technology Comprehensive Report] On July 18, according to The Information, insiders said that SpaceX, a Space exploration technology company owned by Elon Musk, disclosed to some investors that it is expected that the company will achieve revenue of about 8 billion dollars (about 57.3 billion yuan at present) in 2023, about twice the revenue of the previous year...
The coldest summer season for mobile phones: sales halved, inventory backlog, and single machine profits of tens of yuan
source |Tech Planetwriting |Wang Linsource |Figure insect creativityZhang Xiaofeng, who runs a mobile phone store in Inner Mongolia, did not welcome the expected summer. In the past, summer was one of the best-selling seasons for mobile phone brands (followed by winter vacation), with Q2 selling over 100 million phones throughout the summer at its peak...
9 articles were exploded from the factory! The Affiliated Hospital of Jining Medical University and the Second Affiliated Hospital of Lian Medical University will withdraw their papers
withdraw a contributionreal-time infoOfficial WeChatFor more exciting content, please contactPaper InformationIn December 2019, the Affiliated Hospital of Jining Medical University and the Second Affiliated Hospital of Dalian Medical UniversityEuropean review for formal and pharmaceutical sciences (Zone 3.3000/4)The title published online in the journal isEffectofatorvastatininpulmonaryarterialhypertensiinratthroughPI3K/AKTsignalingpathway(The effect of Atorvastatin on pulmonary hypertension in rats through PI3K/AKT signaling pathway)...
Astronaut Chen Dong has been undergoing closed training for 6 years, and the teacher has published a newspaper to search for and give birth to twin boys with his wife
In 2016, the Shenzhou 11 manned spacecraft won the sky. After the fairing was thrown away, the commander Jing Haipeng asked Chen Dong:Are you feeling goodCurious about the vast starry sky, Chen Dong couldn't conceal his excitement and loudly replied:CoolAt that time, Chen Dong was still a novice in exploring the universe...
Pressure Test Report on Elasticsearch with Different Slice Settings
850Elasticsearchv7.7...
Is the collective pressure on the White House to relax sanctions a conscience finding among the three major semiconductor companies in the United States? Intentionally sinister?
A very unusual news broke out the other day, but it seems that everyone is not paying much attention. But I think this matter is significant!It is reasonable to say that the three US semiconductor giants are the forces that most want to bring down China's Semiconductor industry, but these three semiconductor giants have collectively pressed the White House to relax the sanctions ban...
You dare to follow the old path of Samsung! The aviation giant would rather go bankrupt than compromise with China!
Before reading the article, please kindly click on "Follow" to facilitate discussion and sharing. In order to give back your support, I will update high-quality content every dayWen|Jiang RanEdit|Jiang RanprefaceFollowing Samsung in South Korea, another foreign company has refused to cooperate with China...
Wearing stockings and waiting for me ", the work group is displaying indecent information! The company claims to have been invaded by a virus, but network security experts say it is unlikely
On July 15th, a screenshot of a WeChat chat was widely circulated online and attracted widespread attention.A screenshot of the online chat shows that at 10:07 pm, a person named "Provincial Government Office" sent three indecent messages in a row: "Has your husband gone out yet?" "Wait for me to go to your house?" "Wear stockings and wait for me...
Fly into the night sky in a straight line! Many netizens witnessed "Unidentified flying object"! The latest research and judgment
At 20:40 on July 14, Zhengzhong Village, Wangfu Township, Chun'an County, Hangzhou City. A netizen posted a video saying that 22 Unidentified flying object were found in the night sky, flying from the side of the mountains to the sky, and disappeared from front to back after flying into the middle of the night sky...