New breakthroughs have been made in tumor marker detection! Chongqing university students develop the first domestic testing instrument

Source: [Chongqing Daily Network]The project team of Surface plasmon resonance Imaging Analysis (SPRI) instrument (hereinafter referred to as SPRI instrument) of Chongqing Medical University won the first prize in the fifth "Five Small" Innovation Competition of Chongqing Health System. Respondent provided picturesOn July 12, the reporter of Chongqing Daily learned that the project team of Surface plasmon resonance Imaging Analysis (SPRI) instrument (hereinafter referred to as SPRI instrument) from the University Town Hospital affiliated to Chongqing Medical University (the Fourth Clinical College of Chongqing Medical University) won the first prize in the just concluded fifth "Five Small" Innovation Competition of Chongqing Health System

Source: [Chongqing Daily Network]

The project team of Surface plasmon resonance Imaging Analysis (SPRI) instrument (hereinafter referred to as SPRI instrument) of Chongqing Medical University won the first prize in the fifth "Five Small" Innovation Competition of Chongqing Health System. Respondent provided pictures

On July 12, the reporter of Chongqing Daily learned that the project team of Surface plasmon resonance Imaging Analysis (SPRI) instrument (hereinafter referred to as SPRI instrument) from the University Town Hospital affiliated to Chongqing Medical University (the Fourth Clinical College of Chongqing Medical University) won the first prize in the just concluded fifth "Five Small" Innovation Competition of Chongqing Health System. Next, the team will also represent the school to participate in the 9th China International "Internet plus" Undergraduate Innovation and Entrepreneurship Competition in Chongqing.

Recently, at Chongqing Traditional Chinese Medicine Hospital, laboratory doctor Shen Bo was using a machine to detect tumor markers in patients. After 30 minutes, the test results were presented on the computer screen. Compared to traditional detection methods in the past, this' big guy 'can really improve our detection efficiency and accuracy, "Shen Bo exclaimed.

The SPRI instrument project team of Chongqing Medical University is doing research on this project. Respondent provided pictures

Shenbo uses the SPRI instrument, which can help doctors detect various tumor markers such as leukemia and lung cancer in the early stages.

"At present, the first generation of Surface plasmon resonance (SPR) technology is used for the detection of tumor markers produced in China, which has the disadvantages of being unable to image, low detection flux and narrow application range. The latest SPRI instrument relies on imports, which is not only expensive, but also has the problems of low flux and poor sensitivity." The student Team leader Zheng Xia, a postgraduate majoring in clinical laboratory diagnostics in the Fourth Clinical School of Chongqing Medical University, introduced that their team, based on the research and development idea of combining medicine with engineering, and relying on international cooperation, school enterprise cooperation, and intra school cooperation, overcame a series of technical problems such as the construction of SPR imaging detection system, array production, glass controlled etching, and vacuum coating, and independently developed the first domestic SPRI instrument, thus breaking the foreign monopoly.

The SPRI instrument project team of Chongqing Medical University is doing research on this project. Respondent provided pictures

The project guidance teacher Xue Jianjiang, director of the Laboratory Department of the Affiliated University City Hospital of Chongqing Medical University, introduced that this instrument has solved the technical problem of traditional SPR technology being unable to image for the first time; Taking the lead in overcoming the world-class challenge of replacing laser light sources with LED light sources; It can simultaneously achieve flux detection for over 100 samples, with a sensitivity higher than 95%. In addition to the combined early screening of tumor markers, this instrument is expected to be applied in areas such as hypertension drug screening, pollutant detection, and neonatal genetic disease gene screening

At present, the SPRI instrument has been qualified and verified by the Chongqing Medical Device Quality Inspection Center, forming a patent technology barrier. It has also been clinically piloted in Chongqing Traditional Chinese Medicine Hospital and Major Cancer Hospital for the detection of tumor markers for leukemia and lung cancer.

This article is from Chongqing Daily website and only represents the author's viewpoint. The National Party Media Information Public Platform provides information dissemination and dissemination services.

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