Progress in research on broad-spectrum disease resistance genes in rice in China

Xinhua News Agency, Wuhan, June 15 (Reporter Li Wei, Xiong Xianghe) The reporter learned from Huazhong Agricultural University that Professor Li Guotian's team had discovered a new rice broad-spectrum disease resistance gene RBL12. The field experiment results showed that RBL12 could recover about 40% of the yield loss in the case of rice blast disease in the field

Xinhua News Agency, Wuhan, June 15 (Reporter Li Wei, Xiong Xianghe) The reporter learned from Huazhong Agricultural University that Professor Li Guotian's team had discovered a new rice broad-spectrum disease resistance gene RBL12. The field experiment results showed that RBL12 could recover about 40% of the yield loss in the case of rice blast disease in the field. This achievement was recently published online in the international academic journal Nature.

Rice blast, known as "rice cancer", is a devastating fungal disease. The global rice yield loss caused by rice blast is tens of millions of tons every year. At present, there are limited varieties of rice with broad-spectrum disease resistance, and the prevention and control measures are still mainly based on drug control. "Li Guotian said that cultivating broad-spectrum disease resistant rice varieties is an effective measure to achieve green prevention and control of crop diseases.

Li Guotian's research team spent 10 years studying rice disease spot like mutants and discovered the mechanism of phospholipid metabolism involved in rice disease resistance. Based on theoretical breakthroughs, the research team discovered a new rice broad-spectrum disease resistance gene RBL12 through gene editing technology.

"Compared with the traditional disease resistance gene, RBL12 is resistant to a variety of pathogens and has a broad spectrum. The gene has excellent resistance to blast in the field." Li Guotian said that after preliminary tests, the gene also has significant effects on wheat rust resistance and Sheath blight of rice resistance. Next, we will continue to systematically analyze the molecular mechanisms of rice disease resistance and growth, and develop new crop germplasm resources with breeding value

The reviewers of Nature magazine believe that this study proposes a new strategy for utilizing reserve resources, which is a significant practical discovery with great potential for application.

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