Gene editing enables chickens to gain resistance to avian influenza

According to a biotechnology concept validation study published on the 10th in Nature Communications, scientists have successfully developed chickens with partial resistance to avian influenza using gene editing technology.Scientists have edited the ANP32A gene in chicken germ cells to limit the activity of influenza A

According to a biotechnology concept validation study published on the 10th in Nature Communications, scientists have successfully developed chickens with partial resistance to avian influenza using gene editing technology.

Scientists have edited the ANP32A gene in chicken germ cells to limit the activity of influenza A. They found that chickens that have fully grown from this have resistance to physiological doses of influenza A from other infected birds and are more resilient. However, genetically edited chickens have no resistance to doses greater than 1000 times. After more than two years of monitoring, the health or egg laying rate of these chickens have not been affected by any adverse effects. The research team proposes that further editing and deletion of other related genes (ANP32B and ANP32E) will prevent virus replication. (Science and Technology Daily reporter Zhang Mengran, photo source: Nature Communications)

Source: Science and Technology Daily

Disclaimer: The content of this article is sourced from the internet. The copyright of the text, images, and other materials belongs to the original author. The platform reprints the materials for the purpose of conveying more information. The content of the article is for reference and learning only, and should not be used for commercial purposes. If it infringes on your legitimate rights and interests, please contact us promptly and we will handle it as soon as possible! We respect copyright and are committed to protecting it. Thank you for sharing.(Email:[email protected])